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In a head-to-head trial in adults with obesity or overweight without diabetes, tirzepatide, the active ingredient in Mounjaro and Zepbound led to greater average weight loss than semaglutide over 72 weeks.However, there are various factors to consider when determining which medication is the best fit for an individual's unique needs including cost and insurance coverage, overall health, side effects, and how well the medication aligns with one's lifestyle and goals

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Per CMS guidelines, BMI codes are secondary diagnoses only and must be supported by a physicians documentation of the associated condition

The list price of semaglutide 0.25mg, 0.5mg and 1mg is 73.25 per pack (four pre-filled pens) excluding VAT